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java.lang.Object org.simBio.core.Component org.simBio.core.Parameter org.simBio.core.Composite org.simBio.core.Reactor org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter org.simBio.bio.terashima_et_al_2006.current.cf.CfChannel org.simBio.bio.terashima_et_al_2006.current.cf.ICFTR
public class ICFTR
Cystic fibrosis transmembrane conductance regulator Cl- channel current.
Field Summary | |
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Node |
ATP
concentration of intracellular ATP [mM] |
Node |
cAMP
concentration of intracellular cAMP [mM] |
Node |
cPKA
fraction of cAMP-activated PKA |
Node |
Isoprenaline
concentration of extracellular isoprenaline [uM] |
double |
kd
dissociation constant of cAMP for PKA activation [mM] |
double |
n
Hill coefficient |
Node |
POpen
open probability |
Fields inherited from class org.simBio.bio.terashima_et_al_2006.current.cf.CfChannel |
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Cm, constantFieldCa, constantFieldCl, constantFieldK, constantFieldNa, permeabilityCa, permeabilityCl, permeabilityK, permeabilityNa, pOpen |
Fields inherited from class org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter |
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cCl, CCl, currentCl |
Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter |
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cCa, CCa, cK, CK, cNa, CNa, current, currentCa, currentK, currentNa, total |
Fields inherited from class org.simBio.core.Parameter |
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value |
Constructor Summary | |
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ICFTR()
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Method Summary | |
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protected void |
calculate(double t)
add Cl current to Compartment. |
Methods inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter |
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prepare |
Methods inherited from class org.simBio.core.Composite |
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accept, getLink, getNode, getNodesIterator, getNodesSize |
Methods inherited from class org.simBio.core.Parameter |
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addValue, getValue, getValueString, setInitializer, setValue, setValueString, setValueToField |
Methods inherited from class org.simBio.core.Component |
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addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks |
Methods inherited from class java.lang.Object |
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clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait |
Methods inherited from interface org.simBio.core.Node |
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addDydt, addValue, getValue, setValue |
Field Detail |
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public Node ATP
public double kd
public double n
public Node POpen
public Node cAMP
public Node cPKA
public Node Isoprenaline
Constructor Detail |
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public ICFTR()
Method Detail |
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protected void calculate(double t)
MembraneTransporter
calculate
in class CfChannel
t
- timeCfChannel.calculate(double)
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