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java.lang.Object org.simBio.core.Component org.simBio.core.Parameter org.simBio.core.Composite org.simBio.core.Reactor org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter org.simBio.bio.takeuchi_et_al_2006.current.CfChannel org.simBio.bio.takeuchi_et_al_2006.current.ICaL
public class ICaL
L-type Ca channel. voltage gated, 4 state voltage gate, from Shirokov et al. 1993, 4 state Calcium gate, from Shirokov et al. 1993, ultra-slow inactivation, ATP Dependency from Noma& Shibasaki 1985 J.Physiol,363:441-462 The amplitude of this channel can be dynamically changed.
ICaL
Field Summary | |
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Node |
ATP
intracellular ATP concentration (mM) |
Node |
CaDiadic
local Ca2+ concentration near the mouth of L-type Ca channel (mM) |
Node |
Cai
intracellular Ca2+ concentration (mM) |
Node |
gate
ultra-slow gate probability |
double |
HillATP
Hill constant of ATP dependency. |
double |
KmATP
Michaelis constant of ATP dependency. |
Node |
pAI
AI state probability for voltage-dependent gate |
Node |
pAP
AP state probability for voltage-dependent gate |
Node |
pC
C state probability for Ca2+-dependent gate |
double |
PKToPCa
ratio of K+ to Ca2+ permeability |
double |
PNaToPCa
ratio of Na+ to Ca2+ permeability |
Node |
pRP
PR state probability for voltage-dependent gate |
Node |
pU
U state probability for Ca2+-dependent gate |
Node |
pUCa
UCa state probability for Ca2+-dependent gate |
Node |
Vm
membrane potential (mV) |
Fields inherited from class org.simBio.bio.takeuchi_et_al_2006.current.CfChannel |
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Cm, constantFieldCa, constantFieldCl, constantFieldK, constantFieldNa, permeabilityCa, permeabilityCl, permeabilityK, permeabilityNa, pOpen |
Fields inherited from class org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter |
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cCl, CCl, currentCl |
Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter |
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cCa, CCa, cK, CK, cNa, CNa, current, currentCa, currentK, currentNa, total |
Fields inherited from class org.simBio.core.Parameter |
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value |
Constructor Summary | |
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ICaL()
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Method Summary | |
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protected void |
calculate(double t)
add Cl current to Compartment. |
Methods inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter |
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prepare |
Methods inherited from class org.simBio.core.Composite |
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accept, getLink, getNode, getNodesIterator, getNodesSize |
Methods inherited from class org.simBio.core.Parameter |
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addValue, getValue, getValueString, setInitializer, setValue, setValueString, setValueToField |
Methods inherited from class org.simBio.core.Component |
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addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks |
Methods inherited from class java.lang.Object |
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clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait |
Methods inherited from interface org.simBio.core.Node |
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addDydt, addValue, getValue, setValue |
Field Detail |
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public Node Vm
public Node pRP
public Node pAP
public Node pAI
public Node CaDiadic
public Node Cai
public Node pC
public Node pU
public Node pUCa
public Node gate
public Node ATP
public double KmATP
public double HillATP
public double PNaToPCa
public double PKToPCa
Constructor Detail |
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public ICaL()
Method Detail |
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protected void calculate(double t)
MembraneTransporter
calculate
in class CfChannel
t
- time
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