org.simBio.bio.takeuchi_et_al_2006.current
Class ICaL

java.lang.Object
  extended by org.simBio.core.Component
      extended by org.simBio.core.Parameter
          extended by org.simBio.core.Composite
              extended by org.simBio.core.Reactor
                  extended by org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter
                      extended by org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter
                          extended by org.simBio.bio.takeuchi_et_al_2006.current.CfChannel
                              extended by org.simBio.bio.takeuchi_et_al_2006.current.ICaL
All Implemented Interfaces:
Node

public class ICaL
extends CfChannel

L-type Ca channel. voltage gated, 4 state voltage gate, from Shirokov et al. 1993, 4 state Calcium gate, from Shirokov et al. 1993, ultra-slow inactivation, ATP Dependency from Noma& Shibasaki 1985 J.Physiol,363:441-462 The amplitude of this channel can be dynamically changed.

Version:
$Id: ICaL.java,v 1.1 2006/11/17 08:08:04 atakeuchi Exp $
Author:
Ayako Takeuchi.
See Also:
ICaL

Field Summary
 Node ATP
          intracellular ATP concentration (mM)
 Node CaDiadic
          local Ca2+ concentration near the mouth of L-type Ca channel (mM)
 Node Cai
          intracellular Ca2+ concentration (mM)
 Node gate
          ultra-slow gate probability
 double HillATP
          Hill constant of ATP dependency.
 double KmATP
          Michaelis constant of ATP dependency.
 Node pAI
          AI state probability for voltage-dependent gate
 Node pAP
          AP state probability for voltage-dependent gate
 Node pC
          C state probability for Ca2+-dependent gate
 double PKToPCa
          ratio of K+ to Ca2+ permeability
 double PNaToPCa
          ratio of Na+ to Ca2+ permeability
 Node pRP
          PR state probability for voltage-dependent gate
 Node pU
          U state probability for Ca2+-dependent gate
 Node pUCa
          UCa state probability for Ca2+-dependent gate
 Node Vm
          membrane potential (mV)
 
Fields inherited from class org.simBio.bio.takeuchi_et_al_2006.current.CfChannel
Cm, constantFieldCa, constantFieldCl, constantFieldK, constantFieldNa, permeabilityCa, permeabilityCl, permeabilityK, permeabilityNa, pOpen
 
Fields inherited from class org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter
cCl, CCl, currentCl
 
Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter
cCa, CCa, cK, CK, cNa, CNa, current, currentCa, currentK, currentNa, total
 
Fields inherited from class org.simBio.core.Parameter
value
 
Constructor Summary
ICaL()
           
 
Method Summary
protected  void calculate(double t)
          add Cl current to Compartment.
 
Methods inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter
prepare
 
Methods inherited from class org.simBio.core.Composite
accept, getLink, getNode, getNodesIterator, getNodesSize
 
Methods inherited from class org.simBio.core.Parameter
addValue, getValue, getValueString, setInitializer, setValue, setValueString, setValueToField
 
Methods inherited from class org.simBio.core.Component
addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks
 
Methods inherited from class java.lang.Object
clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait
 
Methods inherited from interface org.simBio.core.Node
addDydt, addValue, getValue, setValue
 

Field Detail

Vm

public Node Vm
membrane potential (mV)


pRP

public Node pRP
PR state probability for voltage-dependent gate


pAP

public Node pAP
AP state probability for voltage-dependent gate


pAI

public Node pAI
AI state probability for voltage-dependent gate


CaDiadic

public Node CaDiadic
local Ca2+ concentration near the mouth of L-type Ca channel (mM)


Cai

public Node Cai
intracellular Ca2+ concentration (mM)


pC

public Node pC
C state probability for Ca2+-dependent gate


pU

public Node pU
U state probability for Ca2+-dependent gate


pUCa

public Node pUCa
UCa state probability for Ca2+-dependent gate


gate

public Node gate
ultra-slow gate probability


ATP

public Node ATP
intracellular ATP concentration (mM)


KmATP

public double KmATP
Michaelis constant of ATP dependency.


HillATP

public double HillATP
Hill constant of ATP dependency.


PNaToPCa

public double PNaToPCa
ratio of Na+ to Ca2+ permeability


PKToPCa

public double PKToPCa
ratio of K+ to Ca2+ permeability

Constructor Detail

ICaL

public ICaL()
Method Detail

calculate

protected void calculate(double t)
Description copied from class: MembraneTransporter
add Cl current to Compartment.

Overrides:
calculate in class CfChannel
Parameters:
t - time


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