org.simBio.bio.sarai_et_al_2006.current.cf
Class ICaL

java.lang.Object
  org.simBio.core.Component
      org.simBio.core.Parameter
          org.simBio.core.Composite
              org.simBio.core.Reactor
                  org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter
                      org.simBio.bio.matsuoka_et_al_2003.current.cf.CfChannel
                          org.simBio.bio.sarai_et_al_2006.current.cf.ICaL

All Implemented Interfaces:

Node

public class ICaL
extends CfChannel

L-type Ca channel with amplitude factor.

Version:

$Revision: 1.1 $

Author:

B.J. Kim, Koabaysi

See Also:


Sarai et al, 2006 Advance Publication

Field Summary

double	amplitude amplitude factor
Node	ATP intracellular ATP concentration (mM)
Node	CaDiadic local Ca2+ concentration near the mouth of L-type Ca channel (mM)
Node	Cai intracellular calcium concentration (mM)
Node	gate ultra-slow gate probability
Node	pAI AI state probability for voltage-dependent gate
Node	pAP AP state probability for voltage-dependent gate
Node	pC C state probability for calcium-dependent gate
double	permeabilityCaMax maximum Ca permeability
Node	pRP PR state probability for voltage-dependent gate
Node	pU U state probability for calcium-dependent gate
Node	pUCa UCa state probability for calcium-dependent gate
Node	sumCa integration of ICaL
Node	Vm membrane potential (mV)
double	Vshift a shift of activation potential for 4 state voltage gate

Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.cf.CfChannel

constantFieldCa, constantFieldK, constantFieldNa, permeabilityCa, permeabilityK, permeabilityNa, pOpen

Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter

cCa, CCa, cK, CK, cNa, CNa, current, currentCa, currentK, currentNa, total

Fields inherited from class org.simBio.core.Parameter

value

Constructor Summary

ICaL()

Method Summary

protected void	calculate(double t) add current to Compartment.
protected void	prepare() construct null current

Methods inherited from class org.simBio.core.Composite

accept, getLink, getNode, getNodesIterator, getNodesSize

Methods inherited from class org.simBio.core.Parameter

addValue, getValue, getValueString, setInitializer, setValue, setValueString, setValueToField

Methods inherited from class org.simBio.core.Component

addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks

Methods inherited from class java.lang.Object

clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Methods inherited from interface org.simBio.core.Node

addDydt, addValue, getValue, setValue

Field Detail

amplitude

public double amplitude

amplitude factor

permeabilityCaMax

public double permeabilityCaMax

maximum Ca permeability

Vm

public Node Vm

membrane potential (mV)

Vshift

public double Vshift

a shift of activation potential for 4 state voltage gate

Cai

public Node Cai

intracellular calcium concentration (mM)

ATP

public Node ATP

intracellular ATP concentration (mM)

gate

public Node gate

ultra-slow gate probability

pRP

public Node pRP

PR state probability for voltage-dependent gate

pAP

public Node pAP

AP state probability for voltage-dependent gate

pAI

public Node pAI

AI state probability for voltage-dependent gate

pC

public Node pC

C state probability for calcium-dependent gate

pU

public Node pU

U state probability for calcium-dependent gate

pUCa

public Node pUCa

UCa state probability for calcium-dependent gate

CaDiadic

public Node CaDiadic

local Ca2+ concentration near the mouth of L-type Ca channel (mM)

sumCa

public Node sumCa

integration of ICaL

Constructor Detail

ICaL

public ICaL()

Method Detail

prepare

protected void prepare()

Description copied from class: MembraneTransporter

construct null current

Overrides:

prepare in class MembraneTransporter

See Also:

Component.prepare()

calculate

protected void calculate(double t)

Description copied from class: MembraneTransporter

add current to Compartment.

Overrides:

calculate in class CfChannel

Parameters:

t - time

See Also:

Reactor.calculate(double)