org.simBio.bio.matsuoka_et_al_2003.current.pipette
Class VoltageClamp

java.lang.Object
  org.simBio.core.Component
      org.simBio.core.Parameter
          org.simBio.core.Composite
              org.simBio.core.Reactor
                  org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter
                      org.simBio.bio.matsuoka_et_al_2003.current.pipette.Pipette
                          org.simBio.bio.matsuoka_et_al_2003.current.pipette.VoltageClamp

All Implemented Interfaces:

Node

public class VoltageClamp
extends Pipette

voltage clamp protocol.

Version:

$Revision: 1.1 $

Author:

Nobuaki Sarai

See Also:

XML example,
explanation (Japanese, WORD doc)

Field Summary

double	Cm membrane capacitance
double	holdingPotential basal potential for simulation
Node	observedCurrent current through the cell membrane
double	testPotential designated potential for simulation
Node	timeStep time step for integral calculation
Node	Vm membrane potential

Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.pipette.Pipette

elapsedTime, interval, offset, onset

Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter

cCa, CCa, cK, CK, cNa, CNa, current, currentCa, currentK, currentNa, total

Fields inherited from class org.simBio.core.Parameter

value

Constructor Summary

VoltageClamp()

Method Summary

protected void	calculate(double t) to keep Vm constant, Iext is applied.
protected void	prepare() construct null current

Methods inherited from class org.simBio.core.Composite

accept, getLink, getNode, getNodesIterator, getNodesSize

Methods inherited from class org.simBio.core.Parameter

addValue, getValue, getValueString, setInitializer, setValue, setValueString, setValueToField

Methods inherited from class org.simBio.core.Component

addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks

Methods inherited from class java.lang.Object

clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Methods inherited from interface org.simBio.core.Node

addDydt, addValue, getValue, setValue

Field Detail

observedCurrent

public Node observedCurrent

current through the cell membrane

timeStep

public Node timeStep

time step for integral calculation

Vm

public Node Vm

membrane potential

Cm

public double Cm

membrane capacitance

testPotential

public double testPotential

designated potential for simulation

holdingPotential

public double holdingPotential

basal potential for simulation

Constructor Detail

VoltageClamp

public VoltageClamp()

Method Detail

calculate

protected void calculate(double t)

to keep Vm constant, Iext is applied. Iext = -Itoal - (apply - Vm.getValue()) * Cm / (dt * 4) Ideal voltage clamp condition is assumed.

Overrides:

calculate in class MembraneTransporter

Parameters:

t - time

See Also:

MembraneTransporter.calculate(double)

prepare

protected void prepare()

Description copied from class: MembraneTransporter

construct null current

Overrides:

prepare in class Pipette

See Also:

Component.prepare()