org.simBio.bio.henriquez_et_al_2001
Class GapJunction

java.lang.Object
  org.simBio.core.Component
      org.simBio.core.Parameter
          org.simBio.core.Composite
              org.simBio.core.Reactor
                  org.simBio.bio.henriquez_et_al_2001.GapJunction

All Implemented Interfaces:

Node

public class GapJunction
extends Reactor

Voltage-dependent gap junction model developed by Vogel and Weingart.

Version:

$Id: GapJunction.java,v 1.2 2007/10/24 01:26:05 nsarai Exp $

Author:

Chiaki Oka

See Also:

Vogel R and Weingart R, J Physiol, 1998 , Henriquez AP et al., Biophys J, 2001 , GapJunction.ja.doc (Japanese, WORD doc)

Field Summary

double	Acoef coefficient of rate constant alpha (ms-1)
double	Bcoef coefficient of rate constant beta (ms-1)
MathFunction	fVHL non-linear equation for calculating the voltage across hemichannel at HL state
MathFunction	fVLH non-linear equation for calculating the voltage across hemichannel at LH state
double	GH conductance at high state (pS)
Node	gHH conductance of HH state
Node	gHL conductance of HL state
double	GL conductance at low state (pS)
Node	gLH conductance of LH state
Node	gLL conductance of LL state
Node	nHH fraction of HH state
Node	nHL fraction of HL state
Node	nLH fraction of LH state
Node	nLL fraction of LL state
double	Va potential alpha (mV)
double	Vb potential beta (mV)
double	VH potential at high state (mV)
Node	VHL voltage across hemichannel at HL state (mV)
Node	Vj junctional potential (mV)
double	VL potential at low state (mV)
Node	VLH voltage across hemichannel at LH state (mV)

Fields inherited from class org.simBio.core.Parameter

value

Constructor Summary

GapJunction()

Method Summary

protected void

calculate(double t) calculate the unitary gap junction conductance (pS) which depends on transjunctional voltage

Methods inherited from class org.simBio.core.Composite

accept, getLink, getNode, getNodesIterator, getNodesSize

Methods inherited from class org.simBio.core.Parameter

addValue, getValue, getValueString, prepare, setInitializer, setValue, setValueString, setValueToField

Methods inherited from class org.simBio.core.Component

addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks

Methods inherited from class java.lang.Object

clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Methods inherited from interface org.simBio.core.Node

addDydt, addValue, getValue, setValue

Field Detail

Vj

public Node Vj

junctional potential (mV)

nHH

public Node nHH

fraction of HH state

nLH

public Node nLH

fraction of LH state

nHL

public Node nHL

fraction of HL state

nLL

public Node nLL

fraction of LL state

gHH

public Node gHH

conductance of HH state

gLH

public Node gLH

conductance of LH state

gHL

public Node gHL

conductance of HL state

gLL

public Node gLL

conductance of LL state

VH

public double VH

potential at high state (mV)

VL

public double VL

potential at low state (mV)

GH

public double GH

conductance at high state (pS)

GL

public double GL

conductance at low state (pS)

Acoef

public double Acoef

coefficient of rate constant alpha (ms-1)

Bcoef

public double Bcoef

coefficient of rate constant beta (ms-1)

Va

public double Va

potential alpha (mV)

Vb

public double Vb

potential beta (mV)

VHL

public Node VHL

voltage across hemichannel at HL state (mV)

VLH

public Node VLH

voltage across hemichannel at LH state (mV)

fVLH

public MathFunction fVLH

non-linear equation for calculating the voltage across hemichannel at LH state

fVHL

public MathFunction fVHL

non-linear equation for calculating the voltage across hemichannel at HL state

Constructor Detail

GapJunction

public GapJunction()

Method Detail

calculate

protected void calculate(double t)

calculate the unitary gap junction conductance (pS) which depends on transjunctional voltage

Specified by:

calculate in class Reactor

Parameters:

t - elapsed time (ms)